Some of the patients can be prone to more side effects especially if Estrogen patches are not suited for them. Most common side effects of Estrogen patches are skin irritation, back pain and sometimes headache. Sometimes you will also experience bloating and abdominal cramps but these are very rare side effects. It increases the threat of breast cancer especially when used for over 10 years. 3. It can be very dangerous for women who are more prone to blood clotting. 4. It can give headaches or migraines 5. It increases the threat for endometrial cancer 6. It can destroy the liver With all these advantages and disadvantages presented, it all depends to the person if she wants to have the therapy. This part of the anti estrogen news explains that there are really no health benefits in taking estrogen pills and that the health threats undoubtedly frustrate any menopause benefit of estrogen. There were two top newspapers, which presented articles about this study. The articles were based on an incomplete report given by the NIH. For instance, when a person is using conjugated estrogen, which is commonly used in the United States and falls under the brand name of Premarin, and Cenestine the sufficient intake should fall from .3 to .625 mg/ day. The dosage is entirely different when the person is taking estrogen prepared by using synthetic Estradiol and the brand name is Estrace, research showed that adequate dosage is from .5 to 1 mg/day. While many women are benefited by estrogen during or after menopause, some are found at greater risk for particular diseases if they take it. As researches give more information about estrogen, it may help pinpoint the reasons should those persons take it or not. To most women, the helpful effects of estrogen are far more important than the harmful effects it can give. Therefore, when there is an insufficient estrogen in a woman s body, she is susceptible to any cardiovascular diseases. In order to prevent this, hormone replacement therapy must be made. However, the therapy is only good for women who has estrogen deficiency and wants to prevent her self from having a cardiovascular disease.