However, if a man has many estrogen and progesterone in his body, he may have the identifying characteristics of women. Men who have these hormones in huge amount appear to have bigger than normal male breasts, smaller body mass and some other sexual characteristics of women. Thus, it is important that estrogen and progesterone are of least amount in a male s body. It can be very dangerous for women who are more prone to blood clotting. 4. It can give headaches or migraines 5. It increases the threat for endometrial cancer 6. It can destroy the liver With all these advantages and disadvantages presented, it all depends to the person if she wants to have the therapy. Aside from the aforementioned physical attributes that distinguish women from men, it is also essential in some body functions. Anatomically, women should have normal estrogen in the body for normal functioning. Health researches show that normal estrogen keeps the normal functioning of women s body. The product is sealed tightly and once opened you need to use it immediately. There are various types of Estrogen patches that are suited for your individual needs and depending on the type of disorder that you complaint as well. This is not advisable to apply on the breast area due to some possible complications. Several arguments rise regarding the use of conjugated estrogen, but it was also studied that it can even help in reducing the risk of heart diseases. Due to the great effect that has been brought by estrogen replacement therapy in curing other types of illnesses, this paves the way for the American women to support the use of estrogen replacement therapy to cure the disorder in their estrogen hormones. This is often due to a prolonged intake of Estrogen. The risk will vary on the length of the treatment and the dosage of the Estrogen taken by a patient. Since Estrogen therapy has the long term and the short term period, it must be noted that lower dose of medicine should be taken for the long term in order to reduce the risk.